Noninvasive Methods in Cardiology 2025

Kapitola

Utilizing Astronaut Genomics and Multi-omics Data and Artificial Intelligence to Identify Biomarkers for Enhancing Astronaut Health and Personalized Medicine on Earth („ASTROAIMEDICINE“)

Rok vydání: 2025

https://doi.org/10.5817/CZ.MUNI.M280-0841-2025-3

Abstrakt

The ASTROAIMEDICINE project focuses on leveraging astronaut genomic and multi‑omics data combined with artificial intelligence to identify biomarkers that can predict health risks during spaceflight. The aim is to build the first integrated astronaut genomics database in the United Arab Emirates, enabling the discovery of biomarkers associated with key physiological stressors such as radiation, microgravity, and isolation. The insights gained will support personalized medicine for astronauts and contribute to the development of innovative diagnostic and therapeutic approaches applicable to patients on Earth.

Klíčová slova

astronaut genomics, multi‑omics, biomarkers, artificial intelligence, spaceflight health risks, radiation exposure, microgravity isolation, personalized medicine, astronaut genomics database, ASTROAIMEDICINE


Reference

  1. Goswami Nandu, Blaber Andrew Philip, Valenti Giovanna et al. Gravity, Microgravity, and Artifitial Gravity: Physological Effect, Implementation, and Applications. Physiol Rev. 2026;106(2):751-840. https://doi.org/10.1152/physrev.00055.2024
  2. Goswami Nandu, Singh Akansha, Deepak Kishore Kumar. Developing a „dry lab“ activity using lower body negative pressure to teach physiology. 2021 https://doi.org/10.1152/advan.00123.2020
  3. Goswami N, Blaber AP, Hinghofer-Szalkay H, Convertino VA. Lower Body Negative Pressure: Physiological Effect, Applications, and Implementation. Physiol Rev. 2018; 99(1):807-851. https://doi.org/10.1152/physrev.00006.2018